Cell-Tissue Imaging Post-Doctoral Scholar
The cancer metabolism laboratory of Drs. Teresa Fan, Andrew Lane, and Richard Higashi at the University of Kentucky are seeking a postdoctoral scholar with cell and tissue imaging expertise. Candidates must have broad knowledge of immunofluorescence (IF) and immunohistochemical (IHC) staining of fixed and live cells/tissues with an emphasis on multiplexed/quantitative staining techniques and confocal microscopy. Also required are practical knowledge on lung cancer biology/pathology/metabolism and extensive experience with cell/tissue culturing. Skills in super-resolution and time-lapse-based 4D microscopy are highly desired. The incumbent will participate in a multi-disciplinary lung cancer patient-based project that explores cancer cell and immune cell (macrophage and T cells in particular) interactions in terms of immunomodulatory metabolism in the tumor microenvironment. He or she will contribute to the teamwork by advancing understanding of individual cell contributions to such interactions by performing and developing as needed, IF/IHC methods for quantitative analysis of protein markers for cell lineage, immune/metabolic functions, and their transcriptional regulators. The laboratory is an integral part of the Center for Environmental and Systems Biochemistry (CESB), which is a high technology metabolomics center that develops methodologies for both conventional and stable isotope resolved metabolomics (SIRM), with national and international collaborations and reputation. Salary and benefits are competitive and commensurate with experience. Please send inquiries, curriculum vitae, and contact information for at least three references to: Dr. Teresa Fan, email@example.com.
The University of Kentucky is committed to a policy of providing equal employment opportunities to all candidates regardless of economic or social status and will not discriminate on the basis of race, color, ethnic origin, national origin, creed, religion, political belief, sex, sexual orientation, marital status, or age. For more information, please see http://www.uky.edu/HR/working/
Molecular Biologist Post-Doctoral Scholar
Center for Environmental and Systems Biochemistry (CESB) is recruiting a postdoctoral scholar to work on defining lung cancer and immune cell interactions in the tumor microenvironment with the goal of developing immunometabolism-based therapeutic strategies. This will be accomplished by using systems biochemical approaches including stable isotope-resolved metabolomics (SIRM), reverse phase protein profiling, and transcriptomics such as RNAseq. The incumbent should have expertise in 2D and 3D cancer cell, macrophage, and T cell culturing, animal surgery and tumor implantation skills, gene manipulation techniques (e.g. siRNA, shRNA, or CRISPR), quantitative PCR, confocal microscopic imaging, and protein blotting. Knowledge of cancer metabolic and transcriptomic data analysis is also required. Familiarity with fresh human tissue handling is desired but not required. Training will be provided as needed. We offer competitive package commensurate with experience. Interested applicants should contact Dr. Teresa Fan (firstname.lastname@example.org) or Andrew Lane (email@example.com).
The University of Kentucky is committed to a policy of providing equal employment opportunities to all candidates regardless of economic or social status and will not discriminate on the basis of race, color, ethnic origin, national origin, creed, religion, political belief, sex, sexual orientation, marital status, or age. For more information, please seehttp://www.uky.edu/HR/working/
Staff and Postdoctoral Positions
The University of Kentucky’s Center for Environmental and Systems Biochemistry seeks a Postdoctoral scientist in Mass Spectroscopy. The Center is a high technology core resource that serves the needs of researchers in both conventional and stable isotope resolved metabolomics (SIRM), with national and international collaborations and reputation. In addition to serving the at-large scientific community, the Center conducts metabolomics research directly with Federal and other grants to its directors. Candidates should have knowledge of metabolomics-oriented mass spectrometry technologies and experimental approaches, preferably with experience in coordinating users of shared analytical facilities.
Our mass spectrometry facilities presently include two Thermo Tribrid Fusion Orbitrap instrument, a Thermo Lumos Orbitrap, with Advion Nanomate direct infusion and Dionex IC, Thermo LTQ 1100 GC-MS, A Bruker SolariX 7T ICR spectrometer and an Agilent QQQ ICP-MS.
The incumbent will conduct metabolomics research associated with projects in Lung Cancer Metabolism, which involves very extensive isotope-based data analysis in addition to the expected mass spectrometry skills. Duties will also include helping maintain the instrumentation and associated computer workstations, assist & instruct users on MS analysis, help schedule usage of the instrumentation, direct technical assistants, and assist in manuscript and proposal preparation. The successful candidate will have experience in at least one of the major types of MS instruments, basic MS instrument maintenance and minor repair skills, data system skills preferably with informatics experience, and a Ph.D. in an appropriate discipline. Salary and benefits are competitive and commensurate with experience. Please send inquiries, curriculum vitae, and contact information for three references to: Dr. Richard Higashi, firstname.lastname@example.org. The University of Kentucky is committed to a policy of providing equal employment opportunities to all candidates regardless of economic or social status and will not discriminate on the basis of race, color, ethnic origin, national origin, creed, religion, political belief, sex, sexual orientation, marital status, or age. For more information, please see http://www.uky.edu/HR/working/
Please contact Drs. Fan, Lane and Higashi to discuss opportunities.
- We accept graduate students from the University of Kentucky's IBS Program.
- There are opportunities for undergraduates via the University of Kentucky's STEPS Program.
Lexington as a great place to live!
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- As reported on Kentucky.com in July, 2011, Forbes magazine names Lexington, Kentucky, as the fourth best places for business and careers in a national ranking.