Employment

Cell-Tissue Imaging Post-Doctoral Scholar

The cancer metabolism laboratory of Drs. Teresa Fan, Andrew Lane, and Richard Higashi at the University of Kentucky are seeking a postdoctoral scholar with cell and tissue imaging expertise.  Candidates must have broad knowledge of immunofluorescence (IF) and immunohistochemical (IHC) staining of fixed and live cells/tissues with an emphasis on multiplexed/quantitative staining techniques and confocal microscopy.  Also required are practical knowledge on lung cancer biology/pathology/metabolism and extensive experience with cell/tissue culturing. Skills in super-resolution and time-lapse-based 4D microscopy are highly desired. The incumbent will participate in a multi-disciplinary lung cancer patient-based project that explores cancer cell and immune cell (macrophage and T cells in particular) interactions in terms of immunomodulatory metabolism in the tumor microenvironment. He or she will contribute to the teamwork by advancing understanding of individual cell contributions to such interactions by performing and developing as needed, IF/IHC methods for quantitative analysis of protein markers for cell lineage, immune/metabolic functions, and their transcriptional regulators. The laboratory is an integral part of the Center for Environmental and Systems Biochemistry (CESB), which is a high technology metabolomics center that develops methodologies for both conventional and stable isotope resolved metabolomics (SIRM), with national and international collaborations and reputation. Salary and benefits are competitive and commensurate with experience.  Please send inquiries, curriculum vitae, and contact information for at least three references to: Dr. Teresa Fan, twmfan@gmail.com.

The University of Kentucky is committed to a policy of providing equal employment opportunities to all candidates regardless of economic or social status and will not discriminate on the basis of race, color, ethnic origin, national origin, creed, religion, political belief, sex, sexual orientation, marital status, or age.   For more information, please see http://www.uky.edu/HR/working/

Molecular Biologist Post-Doctoral Scholar

Center for Environmental and Systems Biochemistry (CESB) is recruiting a postdoctoral scholar to work on defining lung cancer and immune cell interactions in the tumor microenvironment with the goal of developing immunometabolism-based therapeutic strategies. This will be accomplished by using systems biochemical approaches including stable isotope-resolved metabolomics (SIRM), reverse phase protein profiling, and transcriptomics such as RNAseq. The incumbent should have expertise in 2D and 3D cancer cell, macrophage, and T cell culturing, animal surgery and tumor implantation skills, gene manipulation techniques (e.g. siRNA, shRNA, or CRISPR), quantitative PCR, confocal microscopic imaging, and protein blotting. Knowledge of cancer metabolic and transcriptomic data analysis is also required. Familiarity with fresh human tissue handling is desired but not required. Training will be provided as needed. We offer competitive package commensurate with experience. Interested applicants should contact Dr. Teresa Fan (twmfan@gmail.com) or Andrew Lane (andrew.lane@uky.edu).

The University of Kentucky is committed to a policy of providing equal employment opportunities to all candidates regardless of economic or social status and will not discriminate on the basis of race, color, ethnic origin, national origin, creed, religion, political belief, sex, sexual orientation, marital status, or age. For more information, please seehttp://www.uky.edu/HR/working/

Staff and Postdoctoral Positions

  • Mass Spectrometrist

    The University of Kentucky’s Center for Environmental and Systems Biochemistry seeks a Postdoctoral scientist in Mass Spectroscopy. The Center is a high technology core resource that serves the needs of researchers in both conventional and stable isotope resolved metabolomics (SIRM), with national and international collaborations and reputation. In addition to serving the at-large scientific community, the Center conducts metabolomics research directly with Federal and other grants to its directors. Candidates should have knowledge of metabolomics-oriented mass spectrometry technologies and experimental approaches, preferably with experience in coordinating users of shared analytical facilities.

    Our mass spectrometry facilities presently include two Thermo Tribrid Fusion Orbitrap instrument, a Thermo Lumos Orbitrap, with Advion Nanomate direct infusion and Dionex IC, Thermo LTQ 1100 GC-MS, A Bruker SolariX 7T ICR spectrometer and an Agilent QQQ ICP-MS.

    The incumbent will conduct metabolomics research associated with projects in Lung Cancer Metabolism, which involves very extensive isotope-based data analysis in addition to the expected mass spectrometry skills. Duties will also include helping maintain the instrumentation and associated computer workstations, assist & instruct users on MS analysis, help schedule usage of the instrumentation, direct technical assistants, and assist in manuscript and proposal preparation. The successful candidate will have experience in at least one of the major types of MS instruments, basic MS instrument maintenance and minor repair skills, data system skills preferably with informatics experience, and a Ph.D. in an appropriate discipline. Salary and benefits are competitive and commensurate with experience. Please send inquiries, curriculum vitae, and contact information for three references to: Dr. Richard Higashi, rick.higashi@uky.edu. The University of Kentucky is committed to a policy of providing equal employment opportunities to all candidates regardless of economic or social status and will not discriminate on the basis of race, color, ethnic origin, national origin, creed, religion, political belief, sex, sexual orientation, marital status, or age. For more information, please see http://www.uky.edu/HR/working/

Student Positions

We are always looking for enthusiastic undergraduate and graduate students that want to learn cutting-edge SIRM methods and research.
Please contact Drs. Fan, Lane and Higashi to discuss opportunities.
  • We accept graduate students from the University of Kentucky's IBS Program.
  • There are opportunities for undergraduates via the University of Kentucky's STEPS Program.

Lexington as a great place to live!

  • According to the April 27, 2009 edition of the Lexington Herald-Leader, Relocate-America has ranked Lexington in the top twelve cities to live in America for 2009. Relocate America states that the average home prices and overall home values have remained very stable. Sales statistics show that the median and mean price of housing has remained virtually unchanged over the last few years. Lexington has many suburban developments that are very well established and desirable places to live throughout the community.
  • According to Business Week - July 10, 2009 edition, Lexington, Kentucky was chosen as one of the top ten most affordable places to retire due to the low property taxes, cost of living, universities, horse farms and the very diverse economy with a mix of agriculture, government, health care and education.
  • According to August 2009 issue of AARP Magazine, Lexington, Kentucky was chosen as the seventh best city to reside for retirement living.
  • In the November 2009 issue of Fortune Magazine, Lexington, Kentucky was chosen as the sixth best medium size cities to launch a new business.
  • According to the April 15, 2010 edition of Forbes.com- Lexington was ranked the ninth best place for business and careers among the 200 largest metro areas in the U.S.
  • The foreclosure rates for Fayette County Kentucky, according to the realty trac is at a rate of one per every 1479 households, which is an 18% decline from October 2010. according to the Mortgage Bankers Association in Kentucky - approximately four percent of the total mortgages in Kentucky are delinquent which is below the national average - currently at 6.8%.
  • Lexington, Kentucky was recently ranked number 5 by the Wall Street Journal for the best markets for investing in the August 2010 report.
  • According to the March 17, 2011, edition of the Lexington Herald-Leader, Manpower Employment Agency states the Lexington's area job market is to be the strongest in the nation in the second quarter of 2011. This is based on 28 percent of local firms expect to be hiring in the second quarter of this year and 65 percent of local firms are going to maintain their current staffing levels.
  • As reported on Kentucky.com in July, 2011, Forbes magazine names Lexington, Kentucky, as the fourth best places for business and careers in a national ranking.
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